Lipids for Biology
Cationic and ionizable lipids
Cationic and ionizable lipids play a central role in modern biological research and therapeutics, especially in the delivery of nucleic acids such as mRNA, siRNA, and DNA. Their positively charged or pH‑responsive headgroups enable them to bind and encapsulate negatively charged genetic material, forming lipid nanoparticles (LNPs) that protect these fragile molecules from degradation and facilitate their entry into cells. Ionizable lipids, in particular, remain neutral at physiological pH—reducing toxicity—but become positively charged in the acidic environment of endosomes, promoting endosomal escape and efficient intracellular release of the therapeutic cargo.
ALC-0315
| Item | Cat. No | Pack | Price |
| ALC-0315 CAS 2036272-55-4 • C48H95NO5 FW 766.3 ℹ️ Ionizable cationic lipid used as a core component of modern mRNA lipid nanoparticles (LNPs), especially in vaccines and gene‑therapy formulations. | 1900 | 100 mg | $460 |
| 500 mg | $1500 |
DODAP Oil
| Item | Cat. No | Pack | Price |
| DODAP Oil CAS 127512-29-2 • C41H77NO4 FW 648.1 ℹ️ Ionizable cationic lipid widely used in lipid nanoparticle (LNP) formulations for nucleic acid delivery. | 1901 | 100 mg | $200 |
| 200 mg | $330 |
